Boris Simončič

Stem Cells in Dentistry: Present – Future
B. Simončič, Z.R. Vulićević, Ž. Rojs

Stem cells are defined functionally as unspecialized cells that have the capacity to self-renew as well as the ability to generate differentiated cells. More explicitly, stem cells can generate daughter cells identical to their mother (self-renewal) as well as produce progeny with more restricted potential (differentiated cells).
The concept of regenerative dentistry is to use stem cells to regenerate or replace damaged oral tissues, processes, which were previously considered irreversible. Restorative treatments have regenerative potential of dental pulp stem cells to give rise to tertiary dentine, which is therapeutically employed for direct and indirect pulp capping. Stem cells in endodontic research have revealed their potential to continue root development in necrotic immature teeth. Transplantation of vital dental pulp in extraction socket enhance the restoration of the alveolar bone.
Stem cells offer a new approach in regenerative treatments. The future of dentistry could see significant improvements in patient care, with stem cells playing a key role in repairing and regenerating oral tissues.

B. Simončič, Faculty of Dentistry, University of Belgrade
Z.R. Vulićević, Faculty of Dentistry, University of Belgrade
Ž. Rojs, Medical Center Mirje, Ljubljana

Boris Simončič, CO of Medical Center Mirje, the Institute for Regenerative and e-medicine in Ljubljana. Honorary Professor at University of Belgrade, Faculty of Dentistry. Founder of Slovenian Association for Osseointegration and an active member of SLovenian and International Dental Associations. Author and coauthor of over 30 scientiffic publications, 50 scientiffic presentations and 2 book chapters from the field of Dental Materials, Periodontology, Implantology and Regenerative Medicine based on Stem Cells.